Volume 37, Number 2
Volume 37 Number 2
Novel Substituted Indazoles towards Potential Antimicrobial Agents
Introduction Due to the omnipresent nature of nitrogen containing heterocycles they are the key scaffolds of many biologically important molecules and pharmaceutical products. These nitrogen atoms containing heterocycles are part of the world’s largest...
Read MoreAntioxidant, a-Amylase Inhibitory Activities and Photoprotective Properties of Peels of Nephelium Lappaceum Linn. (Malwana Special)
Introduction Reactive oxygen species (ROS) in biological systems include superoxide (O2●-), hydroxyl (HO●), singlet oxygen (1O2) and peroxyl (RO2●) radicals1. Reactive oxygen species are generated as byproducts during oxidative metabolism in the mitochondrial electron-transport...
Read MoreDevelopment and Validation of Estimation of Genotoxic Impurity (Hydroxylamine Hydrochloride content) in Leflunomide by using RP-HPLC technique
Introduction Leflunomide (see Figure 1)is an immune-suppressive1disease-modifying anti-rheumatic drug (DMARD)and, mainly use for active moderate-to-severe rheumatoid arthritis2,3 and psoriatic arthritis The chemical name of Leflunomideis a Isoxazolecarboxamide, 5-Methyl-N-[4-(trifluromethyl)-phenyl]. It acts inhibitor of synthesis of...
Read MoreSynthesis, Characterization, Structural Exploration and Quantum Chemical Calculations of (E)-8-(1-((4-Aminobenzyl)imino)ethyl)-7-Hydroxy-4-Methyl-Coumarin
Introduction Coumarin derivatives have been used extensively in several pharmaceuticals due to their diverse biological properties. They have been observed to possess antitumor, antituberculosis, antioxidant, anti-inflammatory, antiviral, and antimicrobial activities 1-6. Several coumarin derivatives...
Read MoreEffect of Ph and Irradiation Power in the Synthesis of Gold Nano particles by Using Binahong (Anredera Cordifolia) Leaves Extract
Introduction Synthesis of gold nanoparticles may follow many kinds of mechanism, such as template– assisted synthesis[1,2], seed-mediated synthesis[3,4], or high frequency energy-assisted synthesis[5,6]. Even though those mechanisms may yield nanoparticles with controlled morphology, however,...
Read MoreKinetic Studies of Adsorption Process of Zambian Kapiri Mposhi Zeolites
Introduction The physical transfer of solute particles or ions from the solution site to the interior of an adsorbent through its pores is called adsorption. The adsorbent used in this study is clay based...
Read MoreReactions of MoOCl4 and MoO2Cl2 with Heterocyclic Thioamides
Introduction 6-Mercaptopurine (IUPAC: 1, 7-dihydro-purine-6-thione) Pyrimidine ring and imidazole ring are fused in purine. 6-mercaptopurine (mpH) has delocalized π-electrons. Nucleophiles can attack at positions 2, 6 and 8. Electrophiles can attack at positions 3 and 7....
Read MoreHigh Energy Density Polyaniline/Exfoliated Graphite Based Supercapacitor with Improved Stability inWide Voltage Window
Introduction Super capacitors are electrical energy harvesting devices that accumulate energy through static charging, typically by electrical double layer capacitance (EDLC) combined with fast Faradaic charge transfer ensuring high power density, fast charging, and...
Read MoreA New Frontier Drug Development in Nanomedicine and Itsanti-Urolithiatic Activity of Kalanchoe Pinnata
Introduction Kidney stone is a most common disease for urinary tract infections. It is the type of disorder which affects the 12% of the population in the world 1-3. At the end stage it...
Read MoreInfluence of Temperature on the Rheological Behavior of Orange Honey
Introduction Honey is a natural product, consumed as food since ancient times [1]. The special status of honey for consumers is due to its natural product image and health benefits [2,3]. After some scandals...
Read MoreCorrosion behavior of GeO2 and Sc2O3 Coatings on AZ31 Alloy
Introduction Magnesium alloys find many applications in space and aerospace applications due to high strength and low density. Even though, they suffer more corrosion due to the more negative electromotive force in the series...
Read MoreQuantification of Lupeol as Secondary Metabolite by HPTLC Technique and Assessment of Antimicrobial Potential of Ethyl Acetate Extract of Betula alnoides Bark
Introduction The herbs containing active ingredients are used for the treatment of various ailments1. Herbs are used traditionally in numerous medicinal system due to their proven beneficial effects on humans2. About 70 to 90%...
Read MoreDetection of Trace Elements in Selective Dairy Products to Assess Human Health Risk of Bangladeshi People
Introduction Milk and milk products are considered to be highly important foods because they contain large quantities of nutritional constituents such as proteins, minerals and vitamins[1]. In our daily diet, milk and milk products...
Read MoreSynthesis, characterization of Novel β-diketone Ni, Fe, Cr Complexes and study of its Antifungal, Antibacterial, Antioxidant and Anti-Inflammatory Activity.
Introduction d-block elements performs crucial part in the development of metal complexes in co-ordination chemistry.Enormous works are exist on the various applications of metal complexes. β-dike tone and their metal complexes perform crucial part...
Read MoreBiosynthesis of Gold Nano particles by Essential Oil of Diplotaxis Acris Characterization and Antimicrobial Activities
Introduction The field of nano science/nanotechnology is a field of research in full expansion which focuses on the elaboration, characterization, application and hazardous effects of new materials with unique or different properties as compared...
Read MoreInvestigation of Metal(II)-Curcumin-Glycine Complexes : Preparation, Structural Characterization and Biological Activities
Introduction Since the cumulative recognition role of metal complexes in biological systems are widely studied in Schiff bases. The ligands are able to coordinate with metals through imine nitrogen and to the aldehyde or...
Read MoreElectrical Conductivity and Ion Exchange Properties of Polyaniline Antimony Tin Tung state Nano composite
Introduction Nano composites are multi component materials consisting of multiple phases in which at least one phase is continuous and has at least one dimension in the nano meter region.Their properties depend on various...
Read MoreAdsorptive Removal of Chromium (VI) Using Silver Nanoparticles Synthesized Via Green Approach with the Extract of Moringa stenopetala
Introduction Background of the study Nanotechnology is a technology that is one of the world’s most innovative approaches. Nanotechnology describes a number of nanometer-scale technologies that range from individual atoms or molecules to around...
Read MoreSustainable Synthesis of Gold Nanoparticles and its Antidiabetic Activity of Anacardium Occidentale
Introduction Diabetes is a metabolic disease which causes the blood sugar level to raise thus by complicating the daily metabolism of life.Phytoconstituents plays a good role in controlling the side effects but the reason...
Read MoreEstimating the Rate of Azithromycin Degradation Due to Heating in Three Drug types by Spectrophotometer (UV) and Gas Chromatography-Mass Spectrometry (GC-MS)
Introduction Azithromycin is a board antibiotic that affects of three various Gram-positive and Gram-negative bacteria, so the azithromycin used for the treatment different of bacterial infections as middle ear infections, strep throat, pneumonia, traveler’s...
Read MorePhysico-Chemical Characterization of Edible Packaging Film Supplemented with Ocimum (Tulsi) Essential Oil
Introduction The numerous benefits of edible packaging such as biodegradable nature, cost effectiveness, being pollution free, potential carrier for antioxidants or antimicrobials, nutritional, safe to consume, good barrier to gases and moisture, shelf life...
Read MorePhysicochemical Analysis of Ground Water Quality, Hydrochemical Characterization of the Doukkala Plain, Morocco
Introduction Morocco classify in the category of countries in a situation of chronic water stress (Water Basin Agency State, OumErrbia Quality, 2016, Morocco). The deterioration of the water quality resources by the increase of...
Read MoreDevelopment and Validation of Estimation of Genotoxic impurity (Triethyl orthoformate content) in 5-methyl – 4 – isoxazole carboxylic acid(5-MIA) by using GC technique
Introduction Leflunomide (see Fig. 1) is an immune-suppressive1 disease-modifying anti-rheumatic drug (DMARD) and, mainly use for active moderate-to-severe rheumatoid arthritis2 and psoriatic arthritis The chemical name of Leflunomide is a 4-isoxazole carboxamide, 5-methyl-N-[4-(trifluromethyl)-phenyl]. It...
Read MoreDowex 50W: A Green Mild Reusable Catalyst for the Synthesis of 2-Aryl Benzoxazole Derivatives in Aqueous Medium
Introduction 2-Substituted benzoxazole derivatives are the main structural features and have immense interest in biologically active pharmaceutical chemistry such as 5-HT3 receptor agonist1, melatonin2, VLA-4 antagonist3 like imidazole3 and benzimidazole3. Benzoxazole derivatives are used...
Read MoreSpectroscopic, Voltammetric, DFT and Molecular Docking Studies of Copper (II) Complex of Carbothiohydrazide Derivative
Introduction Organic dyes are an important class of compounds that attracts much interest because of its wide applications particularly in biotechnology and medical diagnostics.1,2. The structures, spectroscopic properties and chemical reactivates of these dyes...
Read MoreA Headspace Gas Chromatographic Method for Determination of Formic Acid Content in Isosulfan Blue and Various Drug Substances.
Introduction Isosulfan Blue (See Fig. 1) is well known indicator its work like methylene blue. It is a diagnostic agent to detect the cancer cell. Isosulfan Blue is called as [4-[α-[p-(Diethylamino)phenyl]-2,5-disulfobenzylidene]-2,5-cyclohexadien-1-ylidene]diethylammonium hydroxide, inner salt,...
Read MoreA Hashin Criteria Investigation to Predict the Interaction Effect of Defaults on the Damage of Composite Pipe
Introduction Composite pipelines provide a structurally efficient alternative, a solution to pipe development and extension for the oil industry (1)–(2). However their damage by the presence of defects is amplified by the presence and...
Read MoreComparative Dielectric Study of Binary Mixtures of Coriandar oil and Radish oil
Introduction Food is fuel for the body and keeps our mind fit and working. Adulterated food products are responsible for an abundant loss both physically and mentally. With the development in the methods of...
Read MoreUsing of Sukary and Khlass Date Pits as a Bio-adsorbents for Adsorption of Lead and Copper Ions from Waste Water
Introduction Lead and copper are heavy metals among the most harmful of the elemental pollutants because of their toxicities to humans. Main sources of these metals in wastewater are metal plating and industrial waste1...
Read MoreSynthesis of Salicylate and Salicylamide Alcohols for the Preparation of Phosphorodiamidates and Ifosfamide Prodrugs
Introduction Prodrugs are precursors of drug substanceswhich are pharmacologically inactive it necessary either enzymatic alteration or chemically transformation to the main drug in vivo so order as to achieve a pharmacological consequence. Prodrug is...
Read MoreCOVID-19: Challenges, Preventive Measures and Remediation
Introduction Viruses are minuscule parasites and are associating links of living and non-livings. They don’t have any fundamental activities outside of a living cell. Nonetheless, when it interacts with a vulnerable cell, it infects...
Read MoreSynthesis, Characterization and Antimicrobial Activities of bio functionalized Ag and Au Metal Nanoparticles: A Review.
Introduction A nano science technology is a technology to understand and functionalize the material size which is very close to atomic dimension. The physicochemical properties of nano sized material changes from Pico and macro...
Read MoreA Recent Review on Chemistry and Biological Activities of Bryophyllum Pinatum (Lam.) Oken Family: Crassulaceae
Introduction Our traditional medicinal system includes Ayurveda, Siddha and Unani. This Ayurveda concept emerged between 2500-500 BC in India (1). The factual meaning of Ayurveda is “science of long life” and by using different modern...
Read MoreA Review on Nanorods – An Overview from Synthesis to Emerging, Device Applications and Toxicity
Introduction Nanorods Nanoscience, nanotechnology, and nanomaterials are now a central field of science and technological activity.A quick definition of the terms above will give an insight into the subject matter.Nanoscience refers to the study,...
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