Volume 38, Number 6
Volume 38, Number 6
Kinetics and Mechanisms of Ligand-Exchange of Cu(Methionine)2 by Polyamines
Introduction Amino acids are essential ingredients in biological system. Since we are mimicking such systems by reacting metal ions with amino acids in vitro we have avoided chemicals to represent the biological system. Their...
Read MoreDevelopment of a Novel One-Pot Process for the Synthesis of Tolcapone
Introduction Tolcapone an FDA approved drug used for Parkinson’s disease. It inhibits the Enzyme Catechol-O methyltransferase (COMT). By inhibiting COMT, Tolcapone decreases the degradation of levodopa in the periphery, which allows more levodopa to...
Read MoreAntioxidant, Antibacterial and Antifungal Properties of Black Pepper Essential Oil (Piper nigrum Linn) and Molecular Docking and Pharmacokinetic Studies of its’ Major Component.
Introduction Many plant extracts have been use to treat infectious diseases of human for centuries due to their therapeutic properties. Generally, most of the plants bear important chemical compounds called phytochemicals, which can generate...
Read MoreRheological Behavior of Fruit and Vegetable Purees and Tomato Sauce
Introduction Rheology is the science that deals with the study of the flow and deformation of bodies over time under the action of forces applied to them. Dealing with the study of requests and...
Read MoreSynthesis, Spectral Characterization, and Antimicrobial Activity of Two Novel Schiff Bases Derived from Thiosemicarbazide and Mononuclear 3d Transition Metal Complexes
Introduction Treatment modalities and strategies that utilize the latest antifungal medications are imperative [1]. Over a billion people are affected by fungi worldwide, killing more than 1.5 million. Since metallo- drugs can target multiple...
Read MoreAssessment of Micro-Plastics in Domestic Sewage Water Treatment Plants in India
Introduction “MPs are smaller than 5 mm in diameter size synthetic particles”1. Plastics are everywhere and originate in marine environments, surface water, and soils, and can be found in the air we breathe, a...
Read MoreSynthesis of some Schiff Base Derivatives using One Pot Grinding Method and its Biological Activities
Introduction In recent trends, the substituted benzohydrazide analogues is one of the most important aspect in the field of organic synthesis. The hydrazides have been employed as organic reagents for the characterization and derivatization...
Read MoreVertical Distributions of Zn, Cd, Pb, and Cu at Tropical Coastal Sediments: In case of West Coast of Peninsular Malaysia
Introduction Contaminants are defined as inputs of foreign and potentially toxic compounds into the environment where not all contaminants cause pollution as they may exist in trace amounts. Whereas, pollutants such as heavy metals...
Read MoreHPLC Purification of Bio-Actives of Cleome Viscosa and their Anticancer Activity Against Breast Cancer Cell Lines
Introduction Cancer is one of the most vital causes of death worldwide [1, 2]. Its frequency and death rate show its pace of rise in both emerging and developed nations [3, 4]. Cancer incidence...
Read MoreStructural, Spectroscopic, Molecular Docking and Biological Evaluation of some novel Benzofuran Derivatives
Introduction Benzofuran moiety forms a basic structural fascinating unit responsible for the molecule’s wide range of biological applications1. The inherent biological properties in benzofuran scaffold justifies the extensive interest in using benzofuran as building...
Read MoreElectroless Ni-W-P Alloy Deposition on Mildsteel Using Lawsone as Complexing Agent
Introduction Electroless plating, sometimes referred to as chemical plating or auto-catalytic plating, is a non-galvanic plating method that incorporates numerous continuous chemical processes in an aqueous solution without the usage of external electrical power....
Read MoreDevelopment of a Dissolution Method Validation Technique Using UV-Spectrophotometry for Bosutinib 500mg Tablet
Introduction Bosutinib (BTN) is a newly approved antineoplastic agent used against several forms of cancers such as leukemia of white blood cells in patients not responsive to other treatment strategies 1,2. Initially, bosutinib had...
Read MoreColorimetric Detection of Pesticide Residues in Water Using Zinc oxide (ZnO) Nanoparticles
Introduction Pesticide residues occurrence in water systems is one of the persistent environmental problems worldwide which also pose great risk to health and safety. Occurrence of pesticides in water systems are mainly due to...
Read MoreDesigning Modified Graphene Oxide -Epoxy Coatings for Enhancing the Corrosion Resistant Performance of Mild Steel in Sodium Chloride Solution
Introduction Corrosion is a serious problem that causes failure of the equipment and surface damage to the metals. It also causes economic losses 1–3. It cannot be eliminated completely. But it can be reduced...
Read MoreNovel Method Development, Validation and Forced Degradation Studies for the Concurrent Determination of Lamivudine, Tenofovir Disoproxil Fumarate and Doravirine in Active Pharmaceutical Ingredient and Formulation using RP-UPLC
Introduction Lamivudine1-3 (Fig. 1a), chemically known as 4-Amino-1-1[(2R, 5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one. It is a white or almost white powder, soluble in water, sparingly soluble in methanol and practically insoluble in acetone. It has a molecular formula...
Read MoreAmino Acid Profiling of Some Fresh Water Fishes of Manipur
Introduction Manipur’s fresh water fishes are an important part of the state’s fish resources because the majority of the state is made up of hill regions, each of which contains a number of upland...
Read MoreSonochemical Synthesis, Characterization and Molecular Docking of Thiazole and Triazole Tethered Tetra-Substituted Imidazoles.
Introduction The prime quest for synthetic organic chemist is to develop such protocol which favors both economy and environment. In the field of synthetic organic chemistry, green protocols are crucial for saving the depleting...
Read MoreAppraisal of Vitamin D3 Concentration in Dietary Supplement Marketed in Bangladesh Using HPLC
Introduction Fat soluble Vitamin D3 chemically known as (3β,5Z,7E)-9,10 seccocholesta -5,7,10(19)-trien-3-ol (C27H44O, MW-384.64 g/mol) belongs to secosteroids group1. This vitamin is synthesized from 7-dehydrocholestrol endogenously after UV irradiation or intake from diet 2. Potentially...
Read MoreChemical Profile and Biological Activities of Essential oil from Artabortrys hexapetalus (L.f.) Bhandari Grown in Southern Parts of Western Ghats
Introduction The Western Ghats hilly region is home to a large number of highly valuable medicinal plants1. Southern parts of Western Ghats have great diversity of plants with varied ethno medicinal uses and economical...
Read MoreStudies on Polymeric Hydroxy Compounds and the Electro-Coagulation Process for Removing Arsenic from Ground Water
Introduction Arsenic (As) occurs naturally in small amounts (1. 8 mg/kg) in the earth’s crust, and it is well known that it can appear in minerals in a variety of shapes and sizes1–3. Arsenic...
Read MoreBiodegradable Polymer Nanoparticles: Therapeutic Applications and Challenges
Introduction Innovative carriers for the organization of drug atoms, biodegradable nanoparticles (NPs) are a new type of nanotechnology. The arrangement of drug atoms is done using innovative transporters called biodegradable nanoparticles (NPs). Due to...
Read MoreA Facile One-Pot Process for the Synthesis of Stiripentol.
Introduction Globally 50 million peoples affected by neurological disorder i.e. epilepsy. Nearly 80% of people living with epilepsy are in low and middle-income countries. Globally estimated 5 million people are diagnosed with epilepsy each...
Read MoreIsolation and Characterisation of Flavonoids (Rutin) from the Roots of Cadaba Aphylla (Thunb) and Adenia Glauca of Potential in Anti-Oxidant Activity
Introduction Traditional medicinal herbs were the primary supply source in most developing nations. Nowadays, plants are the primary source for developing new drugs and treating a variety of disorders in the field of natural...
Read MorePhytochemical Analysis of Important Lettuces Available in South Indian Region
Introduction Phytochemicals, which are non-nutritive plant compounds, provide disease-preventive qualities. Since they contain non-essential nutrients, they cannot be used by the human body to support a healthy lifestyle. It is common knowledge that plants...
Read MoreValidation of Essential Oils’ Gas Chromatography Mass Spectrometry Compositional Analysis Using System independent parameters; Kovat Index and Fragmentation Pattern
Introduction The separation, identification and quantification of compounds in a mixture when Gas chromatography is used can be generated from the values of the retention time of the eluting compound (Etxebarria, et al, 2009)....
Read MoreRemoval of Therapeutic Drug Diclofenac Pollution by the Acid Digested Carbon of Waste Leathers
Introduction One of the industrial sectors that is growing most quickly is the pharmaceutical one. Pharmaceutical and personal care product (PPCP) production and consumption have both been rising steadily. This causes these toxins to...
Read MoreEquilibrium and Kinetics Adsorption Modelling Comparison of Zn(II) and Fe(II) on Phosphate Modified Oil Palm Empty-Fruit Bunches Bio-Sorbent
Introduction The development of science and technology results in increased usage of heavy metals such as Fe, Zn, Cu, Pb, Hg, Cd, and Cr. Heavy metals are toxic materials that can cause damage to...
Read MoreConcurrent Discriminative Emission Intensity Quantification of Fexofenadine Hydrochloride and Montelukast Sodium
Introduction Allergies were considered sixth most leading cause for chronic illness with millions over the world enduring mild symptoms like cough, rashes, sneezing, hives, runny nose, scratchy throat, itchy eyes and in some...
Read MoreSynthesis, Characterization and Solvent Effect on the Absorption of Carbanionic Sigma Complex
Introduction A super-electrophilic reagent of current interest for SNAr reactions in organic chemistry is CNBFz. It produces derivatives (substitution products) with amines, amino acids, crown ethers, thiols, phenoxides, phenols, etc., and the majority of...
Read MoreElectrochemical and Biological Studies of Synthesized Schiff Base and its Zinc Complex
Introduction Schiff base ligands are azomethine containing functional groups which are easily synthesized through the condensation reaction of carbonyl compounds with primary amines and they are commonly prepared with heat or under acidic and...
Read MorePyrolytic Preparation of Active Carbons from Peanut Shell biomass for Adsorptive Elimination of Fluoride from Groundwater of Shekhawati Region
Introduction Fluorine, which makes up 0.54 % of the earth’s crust, is commonly called a double-edged sword since minimal quantities impair dental growth while excessive amounts cause incurable dental, skeletal, and soft-tissue fluorosis1....
Read MoreNano-Sized Metal Oxides and their Use as a Surface Disinfectant against COVID-19: Review and Perspective
Introduction A novel coronavirus (SARS-CoV-2) was reported in Wuhan, the People’s Republic of China, in December 2019.1 Coronaviruses are a vast group of viral pathogens responsible for many diseases, including respiratory illness .2 This...
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