Synthesis, Characterization, Spectral Studies, Biocidal Activities of Fe (Ii) And Cu (Ii) Complexes of Azo Dye Ligand Derived from Sulfamethoxazole and Substituted P-Cresol

V.A. Modhavadiya

Department of Chemistry, M.M. Science College, Morbi - 363 642 (India)

ABSTRACT:

P-Cresyl acetate (I) has been prepared by acetylation of p-Cresol. Fries migration of (I) yields 2-Acetyl-4-methyl phenol (II). Clemmensen’s reduction of (II) yields 2-Ethyl-4-methyl phenol (III). Diazonium salt (IV) prepared by diazotizatin of sulfamethoxazole. Azo dye ligand 3-ethyl-2-hydroxy-5-methyl-4’-( 5"-methyl-oxazolel-3"-yl ) amino sulphonyl azobenzene (V) has been prepared by coupling of 2-Ethyl-4-methyl phenol (III) with Diazonium salt (IV) at 0-5 0C.By refluxing alcoholic solution of ligand with aqueous solution of metal salts yields azo dye ligand complexes (VI) of ML2 (H2O)2 or ML2 type. They were characterized by elemental analysis, absorption spectra, conductivity measurement, molecular weight determination and magnetic susceptibility measurements. The ligand as well as the metal complex has been screened for their antimicrobial activity against a number of micro organisms.

KEYWORDS:

Synthesis; ligand; metal complexes; characterization; antimicrobial activity

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Copy the following to cite this article: Modhavadiya V. A. Synthesis, Characterization, Spectral Studies, Biocidal Activities of Fe (Ii) And Cu (Ii) Complexes of Azo Dye Ligand Derived from Sulfamethoxazole and Substituted P-Cresol. Orient J Chem 2012;28(2).

Copy the following to cite this URL: Modhavadiya V. A. Synthesis, Characterization, Spectral Studies, Biocidal Activities of Fe (Ii) And Cu (Ii) Complexes of Azo Dye Ligand Derived from Sulfamethoxazole and Substituted P-Cresol. Available from: http://www.orientjchem.org/?p=23479