Synthesis of Hydrazones Schiff Bases and Microbiological Evaluation of Isonicotinoyl Hydrazide with Different Acetophenone

S.R. Kelode¹, P.R. Mandlik¹ and A.S. Aswar²

¹Department of Chemistry, Shri Shivaji Science College, Amravati (India).

²Department of Chemistry, S.G.B. Amravati University, Amravati (India).

ABSTRACT:

A series of hydrazones Schiff bases compounds have been synthesized by reacting isonicotinoyl hydrazide with 2-hydroxy-5-chloro acetophenone, 2-hydroxy-5-methyl acetophenone , 2-hydroxy-5-carboxy acetophenone, 2,5-dihydroxy acetophenone, 2-hydroxy-5-chloro-4-methyl acetophenone, 2-hydroxy-5-chloro-3-nitro acetophenone, 2-hydroxy-5-methyl-3-nitro acetophenone and 2-hydroxy-5-bromo acetophenone. The Schiff bases have been evaluated for the antifungal and antibacterial activities.

KEYWORDS:

Schiff bases; Isonicotinoyl hydrazide; Acetophenone; Antibacterial activities

Download this article as: 

Copy the following to cite this article: Kelode S. R, Mandlik P.R, Aswar A. S. Synthesis of Hydrazones Schiff Bases and Microbiological Evaluation of Isonicotinoyl Hydrazide with Different Acetophenone. Orient J Chem 2011;27(3).

Copy the following to cite this URL: Kelode S. R, Mandlik P.R, Aswar A. S. Synthesis of Hydrazones Schiff Bases and Microbiological Evaluation of Isonicotinoyl Hydrazide with Different Acetophenone. Orient J Chem 2011;27(3). Available from: http://www.orientjchem.org/?p=24516