N-Bromoisonicotinamide: New, Mild, Stable, Effective and Efficient Oxidant for Organic Substrate

M. Balasubramaniyan and N. Mathiyalagan

PG and Research Department of Chemistry, St. Joseph’s College, Tiruchirappalli - 620 002 India.

ABSTRACT:

N-Bromoisonicotinamide (NBIN) is prepared by standard procedure and characterized. The physical constant, the formal redox potential, elemental analysis and spectral characterization (IR and 1H NMR) confirm the presence of nitrogen-halogen bond. It is found to be a stable and mild oxidant of low cost. It is prepared by a simple method, giving high yield in a short period of time. Its formal redox potential shows NBIN can be used as effective source of positive halogen. It will be a valuable addition to the existing oxidants. It is screened for antimicrobial activity against bacteria and fungi at various concentrations using disc diffusion method.

KEYWORDS:

N-Bromoisonicotinamide; oxidant; N-halocompoumds

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Copy the following to cite this article: Balasubramaniyan M, Mathiyalagan N. N-Bromoisonicotinamide: New, Mild, Stable, Effective and Efficient Oxidant for Organic Substrate. Orient J Chem 2010;26(4)..

Copy the following to cite this URL: Balasubramaniyan M, Mathiyalagan N. N-Bromoisonicotinamide: New, Mild, Stable, Effective and Efficient Oxidant for Organic Substrate. Orient J Chem 2010;26(4).Available from: http://www.orientjchem.org/?p=24592