Convenient Synthesis, Characterization of Some Novel Subs-Tituted 3-Methyl-2-Pyrazoline-5-ones and Substituted 3,5-Dimethyl Pyrazoles

ALOK  K.  PAREEK^*, P. E.  JOSEPH and DAYA  S.  SETH

School of Chemical Sciences, Department of Chemistry, ST. John’s College Agra - 282 002 India.

ABSTRACT:

Some of the pyrazolones and pyrazoles bearing different functional groups, substituted pyrazolones were synthesized by the condensation reaction of newly synthesized substituted thio-semicarbazide (1a, 2a) with substituted ethyl aceto hydrazone (a1-g1) in the presence of glacial acetic acid as a catalyst, they are coloured solid, having high melting points. Substituted pyrazoles have been synthesized by the condensation of newly synthesized substituted thiosemicarbazide (1a, 2a) with substituted phenyl benzene-azo acetyl acetone hydrazone (a2 - i2) and glacial acetic acid used as a medium in all condensation reactions. The constitution of the newly synthesized substituted pyrazolones and substituted pyrazoles are characterized by their physical properties, elemental analysis, spectral studies like IR.

KEYWORDS:

Substituted Thiosemicarbazides; Pyrazolones; Pyrazoles; GAA; Synthesis; Characterization; Spectral Analysis

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Copy the following to cite this article: PAREEK A. K, JOSEPH P. E, SETH D. S. Convenient Synthesis, Characterization of Some Novel Subs-Tituted 3-Methyl-2-Pyrazoline-5-ones and Substituted 3,5-Dimethyl Pyrazoles. Orient J Chem 2010;26(4).

Copy the following to cite this URL: PAREEK A. K, JOSEPH P. E, SETH D. S. Convenient Synthesis, Characterization of Some Novel Subs-Tituted 3-Methyl-2-Pyrazoline-5-ones and Substituted 3,5-Dimethyl Pyrazoles. Orient J Chem 2010;26(4). Available from: http://www.orientjchem.org/?p=24268