Separation of thaiamine mononitrate ascorbic acid calcium-D-pantothenate, Niacinamide. pyridoxine hydrochloride and riboflavin by using propyl hydroxy b-cyclodextrin as an ion-pairing reagent

Mohammad Tawkir¹* and S.A. Iqbal²

¹Arts, Commerce and Science College, Tukum, Chandrapur (India).

²Department of Chemistry, Saifia College of Science and Education, Bhopal - 462 001 (India).

ABSTRACT:

The present communication dipics the development of a reversed phase H.P.L C. for the simultaneous estimation of acidic and basic vitamins from solid dosage of polyvitamin and vitamin - B-complex tablets of therapeutic and prophylactic N.F.I. The seperation of vitamins was determined at 280nm. The proposed method is advantageous over reported method, the introduction of propyl hydroxy b-cyclodextrin as an ion-pairing reagent used and found to be profound effect over other ion-pairing reagent. The proposed methods are linear accurate and precise and applicable for daily quality control routine analysis

KEYWORDS:

b-Cyclodextrin; Vitamin - B-complex; Ion-pairing reagent; separation of vitamins

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Copy the following to cite this article: Tawkir M, Iqbal S. A. Separation of thaiamine mononitrate ascorbic acid calcium-D-pantothenate, Niacinamide. pyridoxine hydrochloride and riboflavin by using propyl hydroxy b-cyclodextrin as an ion-pairing reagent. Orient J Chem 2009;25(4).

Copy the following to cite this URL: Tawkir M, Iqbal S. A. Separation of thaiamine mononitrate ascorbic acid calcium-D-pantothenate, Niacinamide. pyridoxine hydrochloride and riboflavin by using propyl hydroxy b-cyclodextrin as an ion-pairing reagent. Orient J Chem 2009;25(4). Available from: http://www.orientjchem.org/?p=22717