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Sio2 Catalyzed Friedlander Synthesis of 1,8-Naphthridines in Dry Media Under Microwave Irradiation

Volume 25, Number 1

K. Mogilaiah*, R. Shiva Prasad and K. Jagadeeshwar

Department of Chemistry,Kakatiya University, Warangal - 506 009 (India).

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ABSTRACT:

2-Aminonicotinaldehyde 1 with various carbonyl compounds containing รก-methylene group 2 undergo Friedlander condensation on the surface of SiO2 when subjected to microwave irradiation generating 1,8-naphthyridines 3 in high yields.

KEYWORDS:

2-Aminonicotinaldehyde; carbonyl compounds containing a-methylene group; Friedlander condensation; 1,8-naphthyridines, SiO2; microwave irradiation

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Mogilaiah K, Prasad R. S, Jagadeeshwar K. Sio2 Catalyzed Friedlander Synthesis of 1,8-Naphthridines in Dry Media Under Microwave Irradiation. Orient J Chem 2009;25(1).

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Mogilaiah K, Prasad R. S, Jagadeeshwar K. Sio2 Catalyzed Friedlander Synthesis of 1,8-Naphthridines in Dry Media Under Microwave Irradiation. Orient J Chem 2009;25(1). Available from: http://www.orientjchem.org/?p=23380

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