Mild and Efficient Synthesis of B-Amino Alcohols by Bismuthtrichloride Catalysed Opening of Epoxides

A. Thirupathaiah¹*, S. Ramanna² and G. Venkateswar Rao²

¹Department of Chemistry, Satavahana University, Karimnagar - 505 001 (India).

²Department of Chemistry, Kakatiya University, Warangal - 506 009 (India).

ABSTRACT:

Nucleophilic opening of epoxides with aniline derivatives in the presence of catalytic amount of bismuthtrichloride in acetonitrile at room temperature afforded the corresponding b-amino alcohols in excellent to very good yield.

KEYWORDS:

Epoxide; bismuthtrichloride; nucleophilic opening; aromatic amine; b-aminoalcohols

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Copy the following to cite this article: Thirupathaiah A, Ramanna S, Rao G. V. Mild and Efficient Synthesis of B-Amino Alcohols by Bismuthtrichloride Catalysed Opening of Epoxides. Orient J Chem 2009;25(1).

Copy the following to cite this URL: Thirupathaiah A, Ramanna S, Rao G. V. Mild and Efficient Synthesis of B-Amino Alcohols by Bismuthtrichloride Catalysed Opening of Epoxides. Orient J Chem 2009;25(1). Available from: http://www.orientjchem.org/?p=23367