Design, synthesis of certain triazole derivatives bearing pyrazine moiety

Prathyusha Vitta, G. Vineela Reddy and R. H. Udupi*

Department of Pharmaceutical Chemistry, N.E.T Pharmacy College, Raichur - 584 103 (India).

ABSTRACT:

Several 4-pyrazinoyl 3 aryl/aryloxy methyl substituted 1,2,4-triazolo (3,4-b) (1,3,4) thiadiazolidine derivatives incorporating pyrazinoyl group have been synthesized. The compounds were screened for in vitro antibacterial,antifungal and antitubercular activities. Some compounds exhibited significant antitubercular and antifungal activity.

KEYWORDS:

Triazole derivatives; pyrazine moiety; N-bridged heterocycles; pathogenic organisms; antitubercular activity

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Copy the following to cite this article: Vitta P, Reddy G. V, Udupi R. H. Design, synthesis of certain triazole derivatives bearing pyrazine moiety. Orient J Chem 2008;24(3).

Copy the following to cite this URL: Vitta P, Reddy G. V, Udupi R. H. Design, synthesis of certain triazole derivatives bearing pyrazine moiety. Orient J Chem 2008;24(3). Available from: http://www.orientjchem.org/?p=24940