Synthesis and Characterization of two Isomers of 2-Methylcyclopentane-1,2,3-Triol

S. S. Lee¹, G. L. David Krupadanam² and Chitneni Prasad Rao¹*

¹Department of Chemistry, Osmania University, Hyderabad- 500 007 (India) ²College of Medicine, National Taiwan University, Taipei - 100, Taiwan (ROC)

2-Methylcyclopent-2-enone (1) was subjected to oxidation with OsO4/ NMO / Py followed by reduction with NaBH4 in methanol to yield two triols which were separated as acetate derivatives (3) and identified from NOE and then hydrolyzed to obtain two triol isomers (4).

Isomers; 2-methylcyclopentane-1;2;3-triol