ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
     FacebookTwitterLinkedinMendeley

Synthesis and Biological Evaluation of Some New 4-(3h) Pyrimidinones

Volume 18, Number 1

J. J. Modha, N. J. Dutta, J. M. Parmar and H. H. Parekh*

Department of Chemistry, Saurashtra University, Rajkot- 360 005 (India)

Article Publishing History
Article Received on :
Article Accepted on :
Article Metrics
ABSTRACT:

The target compounds 2-aroylhydrazino-6-p-chlorophenyl-5-cyano-3-N-methyl-4(3H)-pyrimidinone (4a-o) has been synthesized by the condensation of 6-p-chlorophenyl-5-cyano-2-hydrazino-3-N-methyl-4(3H)-pyrimidinone 3 with different aroyl chlorides. All the products have been evaluated for their antimicrobial activity towards different strains of bacteria and fungi and antitubercular activity towards mycobacterium tuberculosis H37 Rv.

KEYWORDS:

4-(3H)-pyrimidinones; antimicrobial activity; antitubercular activity

Download this article as: 

Copy the following to cite this article:

Modha J. J, Dutta N. J, Parmar J. M, Parekh H. H. Mathur Synthesis and Biological Evaluation of Some New 4-(3h) Pyrimidinones. Orient J Chem 2002;18(1).

Copy the following to cite this URL:

Modha J. J, Dutta N. J, Parmar J. M, Parekh H. H. Mathur Synthesis and Biological Evaluation of Some New 4-(3h) Pyrimidinones. Orient J Chem 2002;18(1). Available from: http://www.orientjchem.org/?p=17002

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

About The Author