Synthesis of New Heterocyclic Di Bromo Chalcone and Quinoxaline Compounds and Their Antibacterial Activity

K. H. Mehta and K. R. Desai

Department of Chemistry, South Gujarat University, Surat-395 007 (India)

Dibromo chalcohnes were prepared by the reaction of chalcone with bromine by using glacial acetic acid and Quinoxalines were prepared by the reaction of dibromo chalcone with benzene-1,2-diamine in presence of concentrated H2SO4 by using ethanol. The intermediate chalcone were synthesized by the reaction of 4-methoxy acetophenone with various aldehydes. The structures of the compounds have been confirmed by elemented analysis and spectral analysis. The antibacterial activity of the compounds have been screened.

Heterocyclic chalcones; Quinoxaline compounds; Antibacterial activity