Synthesis and Biological Activities of Some New Formazans (Part - Ii)

S. D. Bharadwaj

Cancer Hospital and Research Institute, Gwalior- 474 009 (India)

1-phenyl-3 (2 methyl-4-NN'-bis-2' cyanoethylamino phenyl) p-tolyl formazans have been synthesisd by first reacting 4-NN' bis-2-cyanoethylamine-2-methyl benzaldehyde with p-tolyl hydrazide which gave the acid hydrazone. The acid hydrazone on treatment with diazotised aromatic amines in pyridine medium furnished fifteen formazans in 40 to 56% yield. The acid hydrazone and the formazans were found to be devoid of anticancer and anti-HIV activities.

Formazans; Biological activities; Anticancer; Anti HIV activities