Larvicidal Sesquiterpenes and Alkaloids from Goniothalamus Montanus and G. Malayanus (Annonaceae)

G. C. L. Ee, Y. K. Lee, M. Rahmani and Y. H. Taufiq-Yap

Department of Chemistry, Faculty of Science and Environmental Studies, University Putra Malaysia, 43400 Serdang, Selangor Malaysia.

ABSTRACT:

Studies on the larvicidal properties of the leaf extract of Goniothalamus montanus and the stem bark extract of Goniothalamus malayanus have led to the isolation of several bioactive sesquiterpenes and alkaloids. The major sesquiterpenes were identified as a-copaene, alloaromadendrene, a-amorphene, 7-methyl-4-methylene-1-(1-methylethyl)-naphthalene and cadalene. The leaf extract of G. montanus also gave one steroidal triterpene, stigmasterol which was isolated as a major component from the plant. The two alkaloids found to be present in the stem bark extract of Goniothalamus malayanus were ouregidione a 4,5-dioxoaporphine and the phenathrene lactam aristolactam Bll. Goniothalamin, one styryllactone goniothalenol and two acetogenins annonacin and goniothalamicin were also found.

KEYWORDS:

Goniothalamus; montanus; malayanus; styryllactone goniothalenol

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Copy the following to cite this article: Ee G. C. L, Lee Y. K, Rahmani M, Taufiq-Yap Y. H. Larvicidal Sesquiterpenes and Alkaloids from Goniothalamus Montanus and G. Malayanus (Annonaceae). Orient J Chem 2000;16(3).

Copy the following to cite this URL: Ee G. C. L, Lee Y. K, Rahmani M, Taufiq-Yap Y. H. Larvicidal Sesquiterpenes and Alkaloids from Goniothalamus Montanus and G. Malayanus (Annonaceae). Orient J Chem 2000;16(3). Available from: http://www.orientjchem.org/?p=36070