Mass Spectral Studies of Azathioprine Analogues

Ashish K. Tewari¹, Anil Mishra¹ and D. S. Bhakuni²

¹Department of Chemistry, Lucknow University, Lucknow- 226 007 India.

²Medicinal Chemistry Division, CDRI, Lucknow - 226 001 India.

ABSTRACT:

The mass spectral analysis of several analogues of azathioprine has been carried out .The general observation is that the nitroimidazole ring is cleaved first. The C-S-C bond is so labile that the molecular ion peak is not observed by the El technique, however it has been observed by the FD mass technique. A consistent fragmentation pattern has been observed in all the compounds.

KEYWORDS:

azathioprine; nitroimidazole; fragmentation technique

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Copy the following to cite this article: Tewari A. K, Mishra A, Bhakuni D. S. Mass Spectral Studies of Azathioprine Analogues. Orient J Chem 2000;16(2).

Copy the following to cite this URL: Tewari A. K, Mishra A, Bhakuni D. S. Mass Spectral Studies of Azathioprine Analogues. Orient J Chem 2000;16(2). Available from: http://www.orientjchem.org/?p=36289