Synthesis and Antimicrobial Activity of Chalcone Imine Amd its Cyclization by Using Dmso-I2-H2SO4, System

A. W. Raut, A. G. Doshi and P. B. Raghuwanshi

Department of Chemistry, Shri Shivaji Science College, Morshi Road, Amravati-444 602 lndia.

ABSTRACT:

Chalcone condenses with substituted aniline gives chalcone imine .This chalcone imine refluxea m DMSO-I₂ -H₂ SO₄ system affords flavone imine. All these chalcone imine and flavone imine were tested against S. typhi. S paratyphi. P vulgaris, X. spp., F solanri and B. cinema. It is found that the flavone imine are more active than chalcone imine.

KEYWORDS:

Chalcone; chalcone; imine; P vulgaris

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Copy the following to cite this article: Raut A. W, Doshi A. G, Raghuwanshi P. B. Synthesis and Antimicrobial Activity of Chalcone Imine Amd its Cyclization by Using Dmso-I2-H2SO4, System. Orient J Chem 1998;14(2).

Copy the following to cite this URL: Raut A. W, Doshi A. G, Raghuwanshi P. B. Synthesis and Antimicrobial Activity of Chalcone Imine Amd its Cyclization by Using Dmso-I2-H2SO4, System. Orient J Chem 1998;14(2). Available from: http://www.orientjchem.org/?p=22178