Palladium-Catalysed Cyclization of 3- Propargylmercapto-1,2,4 Triazine to Thiazolo [2,3-C][1,2,4]-Triazine

M. M. Heravi*, M. Shafaie and M. Bakavoli

Department of Chemistry, School of Sciences, Ferdowsi University of Mashhad, Mashhad, Islamic Republic of Iran

ABSTRACT:

Selective transformation of 3-propargylmercapto-1.2.4-triazin-5 (2H)-one (1) to 6-methylene-6,7-dihydro-4H-thiazolo [2,3-c] [1,2,4]-triazin-4-one (3) was performed under the condition of Pd (II) salt. Under basic condition the latter was isomerized to a compound which was identified to be 3,6-dimethyl-4H-thiazolo [2.3.-c] [1,2.4]triazin-4-one (4). For definite structure assignment of (4), this compound was unambigiously synthesized and its spectroscopic data were compared with those of (4).

KEYWORDS:

Pd- Catalyzed; Cyclization;' Thiazolotriazine

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Copy the following to cite this article: Heravi M. M, Shafaie M, Bakavoli M. Palladium-Catalysed Cyclization of 3- Propargylmercapto-1,2,4 Triazine to Thiazolo [2,3-C][1,2,4]-Triazine. Orient J Chem 1996;12(1).

Copy the following to cite this URL: Heravi M. M, Shafaie M, Bakavoli M. Palladium-Catalysed Cyclization of 3- Propargylmercapto-1,2,4 Triazine to Thiazolo [2,3-C][1,2,4]-Triazine. Orient J Chem 1996;12(1). Available from:http://www.orientjchem.org/?p=37670