Antimicrobial activity of 1;1 Bis {2-hydroxy-3[1′ H-5′ Aryl pyrazolin-3′-yl methyl phenyl} methane


RAJESH P. GANORKAR¹* and V.S. JAMODE²

¹Department of Chemistry, Mahatma Fule arts, Commerce and Sitaramji Chaudhari Science Mahavidyalaya, Warud, Dist. Amravati - 444 906 (India).

²Ex. Pro V.C. SGB Amravati University, Amravati - 444 902 (India).

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ABSTRACT:

By condensation of hydrazine hydrate with Bis-chalcones in pyridine medium titled Bis- Pyrazolines have been synthesized. Structure of these compounds have been charecterised by spectral analysis. all compounds have been evaluated for their in vitro growth inhibitory activity against different microbes like Staphylococcus aureus, Escherichia coli, Proteus mirabilis and Salmonella typhi. The solutions were prepared in DMF solvents. The culture medium used was nutrient agar medium.

KEYWORDS:

1;1 Bis {2-hydroxy-3[1' H-5' Aryl pyrazolin-3'-yl methyl phenyl} methane; Antimicrobial activity


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