Synthesis and Antimicrobial Properties of Flavone Imines
1Department of Microbiology, Dr. P.D.M. Medical College, Amravati India.
2Ex. Reader Department of Chemistry, Shri Shivaji Science College, Amravati India.
3Ex. Prof. and Head Department of Chemistry Vidyabharti Science College, Amravati India.
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Chalcone condenses with substituted aniline to give chalcone imine. This chalcone imine when refluxed in DMSO-I2-H2SO4 system affords flavone imine. Substituted flavone imines were synthesized and tested for its antimicrobial activity against pathogenic bacteria and fungi. Sensitivity carried out by disc diffusion method displayed good level of antibacterial activity.
KEYWORDS:Flavone imines; Antimicrobial activity
