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Reverse Phase Chromatographic Method of Analysis for Assay and Content Uniformity Estimation of Drug Substance Sitagliptin, Metformin and Empagliflozin from Available Marketed Formulation

Introduction Sitagliptin, metformin drugs are used to treat type 2 [...]

By |2021-09-03T05:28:05+00:00August 30, 2021|Volume 37, Number 4|Comments Off on Reverse Phase Chromatographic Method of Analysis for Assay and Content Uniformity Estimation of Drug Substance Sitagliptin, Metformin and Empagliflozin from Available Marketed Formulation

Development of a Validated High-Performance Liquid Chromatographic Method in Reverse Phase for Simultaneously Determining Triamcinolone Acetonide and Benzyl Alcohol in Injectable Suspension.

Introduction Triamcinolone Acetonide Figure 1 is a synthesized glucocorticosteroid available [...]

By |2021-09-03T05:27:21+00:00August 30, 2021|Volume 37, Number 4|Comments Off on Development of a Validated High-Performance Liquid Chromatographic Method in Reverse Phase for Simultaneously Determining Triamcinolone Acetonide and Benzyl Alcohol in Injectable Suspension.

Stability Indicating RP-HPLC Method Development and Validation for Simultaneous Estimation of Metoprolol Succinate and Chlorthalidone in Bulk and in Tablet Dosage Form

Introduction Metoprolol Succinate (MTL) is chemically, Bis[(2RS)-1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol] butanedioate which is [...]

By |2021-07-02T07:12:52+00:00June 30, 2021|Volume 37, Number 3|Comments Off on Stability Indicating RP-HPLC Method Development and Validation for Simultaneous Estimation of Metoprolol Succinate and Chlorthalidone in Bulk and in Tablet Dosage Form

Viscometric Study of n-Hexylammonium and n-Octylammonium perchlorates in Binary Non-Aqueous Solvents Probed by a Physicochemical Approach in the Temperature Ranging 298 – 328K at Atmospheric Pressure

Introduction Viscosity studies provide adequate information about solvation behavior of [...]

By |2021-08-07T08:27:02+00:00June 30, 2021|Volume 37, Number 3|Comments Off on Viscometric Study of n-Hexylammonium and n-Octylammonium perchlorates in Binary Non-Aqueous Solvents Probed by a Physicochemical Approach in the Temperature Ranging 298 – 328K at Atmospheric Pressure

Development and Validation of Estimation of Genotoxic Impurity (Hydroxylamine Hydrochloride content) in Leflunomide by using RP-HPLC technique

Introduction Leflunomide (see Figure 1)is an immune-suppressive1disease-modifying anti-rheumatic drug (DMARD)and, [...]

By |2021-05-01T09:42:04+00:00April 30, 2021|Volume 37, Number 2|Comments Off on Development and Validation of Estimation of Genotoxic Impurity (Hydroxylamine Hydrochloride content) in Leflunomide by using RP-HPLC technique

Synthesis, Characterization, Structural Exploration and Quantum Chemical Calculations of (E)-8-(1-((4-Aminobenzyl)imino)ethyl)-7-Hydroxy-4-Methyl-Coumarin

Introduction Coumarin derivatives have been used extensively in several pharmaceuticals [...]

By |2021-05-01T09:37:35+00:00April 30, 2021|Volume 37, Number 2|Comments Off on Synthesis, Characterization, Structural Exploration and Quantum Chemical Calculations of (E)-8-(1-((4-Aminobenzyl)imino)ethyl)-7-Hydroxy-4-Methyl-Coumarin

Development and Validation of Estimation of Genotoxic impurity (Triethyl orthoformate content) in 5-methyl – 4 – isoxazole carboxylic acid(5-MIA) by using GC technique

Introduction Leflunomide (see Fig. 1) is an immune-suppressive1 disease-modifying anti-rheumatic [...]

By |2021-05-01T09:48:11+00:00April 30, 2021|Volume 37, Number 2|Comments Off on Development and Validation of Estimation of Genotoxic impurity (Triethyl orthoformate content) in 5-methyl – 4 – isoxazole carboxylic acid(5-MIA) by using GC technique
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