Synthesis of Some New Flavanones by Claisen-Schmidt Condensation


G. R. Subbanwad, M. A. Baseer and Y. B Vibhute

P.G. Department of Chemistry, Yeshwant College. Nanded - 431 602 India.

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ABSTRACT:

A new synthesis of five new flavanones i.e., 6-methyl, 6-chloro, 6-bromo, 6-chloro-7-methyl and 6,8-dichloro-2-(1-naphthyl) chromanone starting from the respective isomeric chalcones prepared by Claisen-Schmidt condensation of substituted 2'-hydroxy acetophenones with 1- naphthaldehyde was carried out. The structure were confirmed by elemental, IR and PMR analysis.

KEYWORDS:

synthesis; flavanones; acetophenones naphthaldehyde


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