Effect of Organophosphate Pesticide Metasystox on the Levels of Dopamine, Norepinephrine and 5-Hydroxytryptamine of Rat Brain

S. Asif Zaidi, Sangita Singh and V. S. Singh

Department of Biochemistry, L, L. R. M. Medical College, Meerut India.

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ABSTRACT:

Metasystox (O, O, dimethyl-S-2 ethylsulphinyl) 4 mg/kg body weight was injected intra peritoneally daily for 10 days. The daily ip dose of Metasystox depleted the levels of Dopamine, Norepinephrine and 5-Hydroxytryptamine in the cerebral hemisphere, cerebellum and brain stem of rat brain.

KEYWORDS:

Organophosphate; Norepinephrine; Brain