Alterations in Amino Acid Neurotransmitters Following the Administration of Organophosphate Pesticide-Metasystox

S. Asif Zaidi, Shalini Pande and V. S. Singh

Department of Biochemistry, L. L. R. M. Medical College, Meerut India.

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ABSTRACT:

Metasystox (O,O, dimethyl-S-2 ethylsulphinyl) 4 mg/kg body weight was injected intraperitoneally (i p) daily for 10 days. The daily i p dose of Metasystox depleted the level of taurine, aspartic acid, glycine, GAEA, serine and lysine in the cerebral hemisphere, cerebellum and brain stem of rat brain.

KEYWORDS:

Neurotransmitters; Administration; Pesticide-Metasystox