One-pot Three-component Coupling Reaction: Solvent-free Synthesis of Novel 2-substituted Aryl (amino) Kojic Acid by pTSA-catalyzed


Mehdi Forouzani1 and Hassan Ghasemnejad-Bosra2

1Department of Chemistry, Payamenoor University, 19395-4697 Tehran, Islamic Republic of Iran.

2Islamic Azad University-Babol Branch, School of Science, P.O. Box 755, Babol, Islamic Republic of Iran.

Corresponding Author E-mail: h_ghasem2000@yahoo.it

DOI : http://dx.doi.org/10.13005/ojc/290226

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ABSTRACT:

p-toluenesulfonic acid (pTSA) catalyzed one-pot synthesis of 2-substituted aryl (amino) kojic acid have been achieved by three component coupling reaction between aldehydes, aniline and kojic acid under solvent free condition in high.

KEYWORDS:

Multi-component reactions; Kojic acid; Aniline; Aldehyde; p-toluenesulfonic acid

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