Microwave Assisted Synthesis of Some Substituted 1,3-diaryl Propenones and 3,5-diaryl-6-carbethoxy Cyclohexenones and their antibacterial activity


Harish Baboo and Sahdev

Department of Chemistry, G. R. P. G. College, Rampur - 244 901, India.

Corresponding Author E-mail: harishbaboo515@gmail.com

DOI : http://dx.doi.org/10.13005/ojc/290215

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ABSTRACT:

Microwave induced solvent free solid phase syntheses of substituted 1,3-diaryl propenones 1a-f using basic alumina and their subsequent rapid transformation to 3,5-diaryl-6-Carbethoxy cyclohexenones 2a-i with ethyl acetoacetate in the presence of basic alumina and piperidine under solvent free condition using domestic microwave oven has been described. These products have been screened for their antibacterial activities.

KEYWORDS:

Microwave solvent free syntheses; 3,5 diaryl-6-Carbethoxy cyelohexenones; antibacterial activity

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