Synthesis and Spectral Study of R,R’,4,4’-Cyclohexylidene Diphenyloxy Acetic acids with Antimicrobial Activity

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Synthesis of R,R’,4,4’-cyclohexylidene diphenyloxy acetic acids ( R,R’= H,CH3and Cl) by dissolving  0.1 mole bisphenols in 0.4 mole sodim hydroxide with drop wise addition  of 0.2 mole chloroacetic acid. The reaction mixture refluxed for 4h at 60°C. Phenoxy acids have been confirmed by IR and NMR spectral characterization. The acids are also characterized by their antimicrobial and antifungal activities. The activities have been interpreted in light of bisphenol structures and the nature of substituent(s). The wide scale uses of bisphenol bioactive agents have brought many advantages to the agricultural industries.

Bisphenol; Phenoxy acetic acids; IR; NMR; Antimicrobial screening