An Efficient One-Pot Synthesis of 1,8-dioxo-Decahydroacridines by Ionic Liquid with Multi-SO3H Groups Under Ambient Temperature in Water
Chemistry Research Laboratory, Faculty of Science, Ayatollah Amoli Branch, Islamic Azad University, Amol (Iran).
Corresponding Author E-mail: m.vahdat@iauamol.ac.ir
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Ionic liquid with multi-SO3H groups was employed as a catalyst for facile preparation of 1,8-dioxo-decahydroacridines via the one-pot condensation of various aldehydes, 1,3-diketones with aromatic amines or ammonium acetate. Various aromatic aldehydes were utilized in the reaction and in all situations the desired product were synthesized successfully. The described novel synthesis method propose several advantages of safety, mild condition, short reaction times, high yields, simplicity and easy workup compared to the traditional method of synthesis.
KEYWORDS:Ionic liquid with multi-SO3H groups; 1,8-dioxo-decahydroacridines; One-pot synthesis; Three component; Water solvent; Chemoselective
