Synthesis and Characterisation of Glimeperide Complexes of Copper, Magnesium, Nickel and Cadmium
1Department of Chemistry, Saifia College of Science and Education, Bhopal - 462001 India.
2Department of Chemistry, Umm-al-Qura University, Makkah-Al-Mukkaramah Saudi Arabia.
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Glimeperide, 3-ethyl-4-methyl-N (4[N(1r, 4r)-4-methyl cyclohexyl carbamoyl) sulfamoyl] phnethyl)-2-Oxo-2, 5-dihydro-1-H-pyrrole-1-Carboxamide the recently used hypoglycemic agent is active in NIDDM. Metal complexes of glimeperide have been synthesized by reaction with different metals such as Copper, Magnesium, Nickel and Cadmium in the form of their chloride salts. These complexes were characterised by their physical and analytical data, IR, 1H NMR and atomic absorption studies.
KEYWORDS:Antidiabetics; Glimeperide; transition metals; 1H NMR; IR; AA-studies
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