Preparation, chemical and biological study of acyclovir analogue starting from 6-aminouracil

Download this article as: 

6-aminouracil14, dibenzosulphonyl ethyl amine¹¹ have been prepared, as starting materials to be introduced as an alkylating reagent with sodium carbonate as catalyst. Acyclovir analogue15 was prepared for the first time, the expected structure of the final newly acyclovir analogue was determined on the basis of NMR, IR, and mass spectroscopy, with low cost, high selectivity, safe and mild reaction conditions.

Chemical and biological study; acyclovir analogue; 6-aminouracil