Novel Synthesis and Characterization of Some New-2-(R) Phenyl- 4-(- 4-Bromo-2-Fluoro Benzylidene)-Oxazol-5-Ones

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Novel Synthesis and Characterization of Some New-2-(R) Phenyl- 4-(- 4-Bromo-2-Fluoro Benzylidene)-Oxazol-5-Ones

Alok K. Pareek^*, P.E. Joseph and Daya S.Seth

School of Chemical Sciences, Department of Chemistry, ST.John’s College Agra - 282 002 India.

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ABSTRACT:

In the present study a series of some new 2-(substituted) phenyl- 4-(4-bromo-2-fluoro benz-ylidene)-oxazol-5-ones (2a-2j) were synthesized by the condensation of selected substituted benzoyl glycine (1a-1j) with 4-bromo-2-fluoro benzaldehyde in the presence of fused sodium acetate and acetic anhydride. The constitution of the newly synthesized compounds has been supported by their physical properties, elemental analysis, colour, m.p, IR spectral analysis data.

KEYWORDS:

Substituted Oxazolones; Substituted Benzoyl Glycines; Substituted Benzalde-Hyde; Synthesis; Characterization; Spectral data