Synthesis of Novel [6,7-B] Indole of Cholestane Series


Azhar U. Khan and M. Mushfiq*

Department of Chemistry Aligarh Muslim University Aligarh (India).

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ABSTRACT:

An efficient synthesis of steroidal indole in one operation by rection of steroidal ketones with phenylhydrazine in acetic acid, using BF3-etherate as catalyst. Compounds obtained are purified by column chromatography and their structure supported by IR, 1HNMR, 13CNMR and MS spectral studies.

KEYWORDS:

Steroids; Steroidal ketones; Steroidal indoles; Indoles


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