Hepatoprotective Potential of Aqueous Extract of Zingiber Officinale Leaves Using Ccl4 Induced Model

Manoj Saurabh; Sarang Jain; Ashish Singha

Article | Open Access

Hepatoprotective Potential of Aqueous Extract of Zingiber Officinale Leaves Using Ccl4 Induced Model

Manoj Saurabh¹*, Sarang Jain² and Ashish Singhai³

¹Department of Pharmacology, Jhalawar Medical College, Jhalawar (India).

²Patel College of Pharmacy, Bhopal (India). ³VNS Institute of Pharmacy, Bhopal (India).

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ABSTRACT:

The hepatoprotective activity of crude aqueous extract of Zingiber officinale leaves (ZOL), Zingiberacae, was evaluated, using CCl4 induced hepatic damage in male Wistar albino rats. Various biochemical parameters like serum glutamic pyruvate transaminase (SGPT), serum glutamic oxaloacetate transaminase (SGOT) and total bilirubin were studied. The aqueous ZOL extract afforded significant protection against CCl4 induced hepatocellular injury.

KEYWORDS:

CCl 4; Zingiber officinale; leaves; extract