Extractive Spectrophotometric Methods for the Determination of Darifenacin

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Two simple and sensitive extractive spectrophotometric methods have been developed for the estimation of Darifenacin in pure and pharmaceutical dosage forms. These methods are based on the formation of ion-pair complexes of the drug with acidic dyes Solochrome black T (SBT: lmax 520 nm) and Methyl Orange (MO: lmax 420 nm). The absorbance of the chloroform extracts is measured against the corresponding reagent blanks. These methods have been statistically evaluated and found to be precise and accurate.

Darifenacin; Spectrophotometric methods; pharmaceutical dosage forms