New Visible Spectrophotometric Method for Estimation of Itopride Hydrochloride from Tablets using Mordant Blue 3 Reagent

B. Choudhary; A. Goyal; S.L. Khokra; D. Kaushik

Article | Open Access

New Visible Spectrophotometric Method for Estimation of Itopride Hydrochloride from Tablets using Mordant Blue 3 Reagent

B. Choudhary¹*, A. Goyal¹, S.L. Khokra² and D. Kaushik²

¹B.N.P.G College of Pharmacy, Udaipur - 313 001 (India).

²Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra - 136 119 (India).

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ABSTRACT:

A simple, precise economical and fast visible spectrophotometric method has been developed for the determination of Itopride hydrochloride in tablet dosage form. Developed is based on formation of extractable colored complex of drug with coloring agent mordant blue 3. A wavelength maximum was found to 471.0 nm. Linearity was observed 30-70 mg /mL. The proposed method describes the determination of Itopride hydrochloride by visible spectrophotometric method which is a precise and selective. The result of analysis have been validated statistically and also by recovery studies.

KEYWORDS:

Visible spectrophotometry; itopride hydrochloride; mordant blue 3