Sio2 Catalyzed Friedlander Synthesis of 1,8-Naphthridines in Dry Media Under Microwave Irradiation

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2-Aminonicotinaldehyde 1 with various carbonyl compounds containing á-methylene group 2 undergo Friedlander condensation on the surface of SiO2 when subjected to microwave irradiation generating 1,8-naphthyridines 3 in high yields.

2-Aminonicotinaldehyde; carbonyl compounds containing a-methylene group; Friedlander condensation; 1,8-naphthyridines, SiO2; microwave irradiation