Mild and Efficient Synthesis of B-Amino Alcohols by Bismuthtrichloride Catalysed Opening of Epoxides

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Nucleophilic opening of epoxides with aniline derivatives in the presence of catalytic amount of bismuthtrichloride in acetonitrile at room temperature afforded the corresponding b-amino alcohols in excellent to very good yield.

Epoxide; bismuthtrichloride; nucleophilic opening; aromatic amine; b-aminoalcohols