Synthesis ,Characterization and Biological Activities of Chalcones and Related Compounds

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Some new chalcones have been prepared by Claisen-Schmidt condensation between various aldehydes and 5’-hydroxyacetophenone. Thiophen-2-aldehyde-5’hydroxyacetophenone(TAHA),furan-2-aldehyde-5’-hydroxy acetophenone(FAHA),2-hydroxynapthaldehyde-5’-hydroxyacetophenone (HNHA)& cinnamalde-5’-hydroxyacetophenone (CAHA) were synthesized & characterised by elemental analyses, IR & NMR spectra. The chalcones were screened for their biological activity.

Synthesis;Biological activity;chalcones