Development and Validation of New Spectroscopic Method for The Estimation of Furazolidone in Bulk and Solid Dosage Form

Dhirender Singh Mittan*, Pradeep Kumar¹, S. P. Venkatesh Prasad¹,Lalit Kumar² and Sudhir Kumar³

¹Department of Pharmaceutical Analysis, PES College of Pharmacy, Bangalore (India).

²Department of Pharmaceutical chemistry, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, (India).

³Hindu College of Pharmacy, Sonepat (India).

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ABSTRACT:

A simple and sensitive spectroscopic method in ultraviolet region was developed and validated for the estimation of Furazolidone in pure and pharmaceutical dosage forms. The method is based on Furazolidone, showing absorbance at 259 nm for zero order derivative spectroscopy respectively in acetonitrile and distilled water. This method obey’s Beers law in the concentration range of 2 to 18 ug/ml respectively. The proposed method is precise, accurate, linear, stable and reproducible and can be extended to the analysis of furazolidone in bulk and tablet formulations.

KEYWORDS:

Furazolidone; UV spectroscopic; U.V; estimation