Microwave-Assisted Synthesis of 3-(2′-Hydroxy-3′-Nitro-5′-Methylphenyl)-5-(Aryl/Heteryl) Isoxazolines


S. B. Borul1, R. U. Pathan2 and S. V. Agarkar3
Anuradha Engineering College, Chikhli-443201 Dist- Buldana India.

2Rahimkhan Usmankhan Pathan, At post- Mangrul Navghare, Tq- Chikhli, Dist- Buldana - 444 301 India.

3Suryakant Bhanudas Borul, At post- Isrul,Tq -Chikhli, Dist- Buldana - 443 201 India.

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ABSTRACT:

The present study deals with the microwave-assisted synthesis and characteristics of 3-(2'-hydroxy-3'-nitro-5'-methylphenyl)-5-(aryl/heteryl) isoxazolines synthesized from 1-(2'-hydroxy-3'-nitro-5'-methylphenyl)-3-aryl/heteryl-2-propen-ones by reaction with hydroxylamine hydrochloride and sodium acetate in ethanol. All synthesized compounds characterized by IR, and NMR.

KEYWORDS:

Microwave; Chalcone; Isoxazoline


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