Synthesis of 3-[6′-Fluoro-7′ Substituted – (1,3′) Benzothiazol- 2′ – Yl] Amino – 2 Substituted – (1,3) Thiazolidin – 4 One for Biological Screening

E. Jayachandran; L. V .G. Nargund; Akhiles Roy; G. M. Sreenivasa; K. Krupanidhi

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Synthesis of 3-[6′-Fluoro-7′ Substituted – (1,3′) Benzothiazol- 2′ – Yl] Amino – 2 Substituted – (1,3) Thiazolidin – 4 One for Biological Screening

E. Jayachandran* L. V. G. Nargund¹, Akhiles Roy, G. M. Sreenivasa and K. Krupanidhi

¹P.G. Department of Pharmaceutical Chemistry S.C.S. College of Pharmacy, Harapanahalli (India) ²Nargund College of Pharmacy Datatreya Nagar B.S.K. 3rd stage Bangalore - 71 (India)

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ABSTRACT:

3-[6'-fluoro-7' substituted - (1,3') benzothiazol - 2' - yl] amino - 2 substituted - (1,3) thiazolidin - 4 - one have been synthesized and evaluated for their antimicrobial activity. Structures of these products have been established by IR, 1HNMR data. Significant antimicrobial activities were observed for some members of this series.

KEYWORDS:

Fluorine; Benzothiazole; Thiazolidinones