Synthesis of 1-[6′-Fluoro-7′ Substituted – (1,3′) Benzothiazol – 2′ – Yl] Amino – 4 – Substituted – 3 Chloro Azetidin – 2 – one for Antimicrobial Screening

E. Jayachandran¹, L. V. G. Nargund², Akhiles Roy¹, G.M. Sreenivasa¹ and K. Krupan¹

¹P.G. Department of Pharmaceutical Chemistry S.C.S. college of Pharmacy Harapanahalli (India) ²Nargund college of pharmacy Datatreya Nagar B.S.K. 3rd Stage Bangalore - 71 (India)

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ABSTRACT:

1-[6'-fluoro-7' substituted - (1,3') benzothiazol - 2' - yl] amino - 4 - substituted - 3 chloro azetidin - 2 - one have been synthesized and evaluated for their antimicrobial activity. Structures of these products have been established by IR, 1HNMR data. Significant antimicrobial activities were observed for some members of this series

KEYWORDS:

Fluorine;L Benzothiazole; Azetidinone