Single Drop Micro Extraction and Determination of Fluoxetine as an Antidepressant from Water Samples by GC-Mass

Z. Modarres-Tehrani¹*, P. Gangipour³, A. Ghiasvand² and J. Mofidi²

¹Department of chemistry, Alzahra University, Vanak street, Tehran (Iran) ²Department of Chemistry, Khoramabad University, Falakolaflak street, Khoramabad (Iran) ³Islamic Azad University, North Tehran branch, Faculty of Chemistry, Tehran (Iran)

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ABSTRACT:

A single-drop micro extraction (SDME) procedure was developed for the analysis of fluoxetine in water by gas chromatography with mass spectrometer detection (GC-MS). The significant parameters affecting the SDME performance such as selection of micro extraction solvent, solvent volume, extraction time, stirring rate, temperature, and ionic strength were studied. The optimum experimental conditions found were: 2.5

KEYWORDS:

solvent micro drop extraction; fluoxetine