An Improved Industrial Process for Synthesis of HMG-Coa Reductase Inhibitor Pitavastatin

S. R. Manne

Article | Open Access

An Improved Industrial Process for Synthesis of HMG-Coa Reductase Inhibitor Pitavastatin

S. R. Manne^1,2

¹Department of Research and Development, MSN Laboratories Limited, Survey No. 317 and 323, Rudraram, Patancheru, Medak District - 502 329 (India) ²Department of Chemistry, P.G. College of Science, Saifabad, Hyderabad (India)

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ABSTRACT:

An highly efficient cost effective, eco-friendly, commercially viable, convergent synthesis for the manufacturing of Pitavastatin, a HMG-CoA reductase inhibitor, has been developed.

KEYWORDS:

Pitavastatin; HMG-CoA reductase inhibitor; E-alkene; syn-diol; Wittig-Horner-Emmons coupling