Synthesis of 6-(2′ Hydroxy-3′ Chloro-5-Hydroxymethyl Phenyl)-4 Aryl/Heteryl 3, 4 Dihydro-2 (1h) Thiopyrimidines

S. V. Agarkar

Head, Department of Chemistry, Anuradha Engineering College, Chikhli, Dist. Buldana-443201 (India)

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ABSTRACT:

The Synthesis of 6-(2-Hydroxy-3' Chloro-5'-hydroxymethly Phenyl)-4 Aryl/Heteryl 3, 4 Dihydro- 2 (1H) - Thiopyrimidines was carried out by refluxing a mixture of 1- (2'-hydroxy -3' chloro-5' hydroxymethyl-phenyl) -3 aryl -2 propen- 1- one (0.01 mol), thiourea (0.01 mol) and KOH (0.01 mol) in methanol (50 ml) for 6 hours.

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