Synthesis and Anticonvulsant Activity of 6-(Substituted Aryl) -2,3,4,5-Tetrahydro-3-Pyridazinones


Anees A. Siddiqui*, Mir Mohammad Shahroz and Mohammad Amir
Department of Pharmaceutical Chemistry, Faculty of Pharmacy Hamdard University, New Delhi- 110 062 (India)

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ABSTRACT:

6-(Substituted aryl)-2,3,4,5-tetrahydro-3-pyridazinones1-8b are obtained from hydrazinolysis of appropriated b-(substituted aroyl) propionic acid. The title compounds showed promising anticonvulsant activity when evaluated by Electroconvulsometer.

KEYWORDS:

Pyridazinone; Anticonvulsant activity


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