Acetanilide Sulphonyl Hydrazides and Hydrazones of Biological Activity

A. Badawi, Kh. A. El-Bayouki* and V. R. Zakaria

Centre of Science and Mathematics, Taif, Saudia Arabia.

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ABSTRACT:

Condensation of various sulphonyl chloride acetanilides with hydrazine hydrate to give the corresponding hydrazides was carried out. Direct condensation between sulphonyl hydrazides and carbonyl compounds (different aldehydes and ketones) to obtain their hydrazones was also attempted. For possible antimicrobial activity; the antibacterial and antifungal activities of the prepared compounds were tested.

KEYWORDS:

Sulphonyl; Biological; Condensation