Synthesis and Antibacterial Activity of Some New Anils, 4-Thiazolidinones and 2-Azetidinones


N. M. Andurkar1, R. P. Pawar2 and Y. B. Vibhute1*
1Post Graduate Department of Chemistry, Dnyanopasak College, Parbhani - 431 401 (India) 2Post Graduate Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (India)

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ABSTRACT:

Some new anils(1) were synthesized in good yield from substituted acetpohenones and Aromatic amines. Further these anils were converted into 4- thiazolidinones(2) and 2-azetidinones(3) by the action of mercaptoacetic acid and chloroacetyle chloride respectively. Structure elucidation of compounds (1), (2) and (3) has been done by elemental analysis, IR and 1H NMR data. All the synthesised compound were screened for their antibacterial activity.

KEYWORDS:

Substituted thiazolidinones; azetidinones; Some new anils


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