Synthesis, Spectral Nature and Antifungal Activity of Di (P-Chloro Phenyl)-Thiosemicarbazone and its Cr(Iii) and Co(Ii) Metal Complexes


Sulekh Chandra, Umendra Kumar and H. S. Verma*
1Department of Chemistry, Zakir Hussain College, University of Delhi, New Delhi (India) 2Department of Chemistry, J.V. (P.G.) College, Baruat, District Bagpat- 250 611 (India)

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ABSTRACT:

The preparation, characterization and antifungal activities of some chromium(III) and cobalt(II) complexes of ligand having nitrogen/sulphur donor set (DPCPTSC) described. Metal complexes have been characterized by spectroscopic studies (I.R., 1H-NMR, electronic and E.S.R.). The free ligand and metal complexes have been tested in vitro against a of pathogenic fungi and were found to possess good fungicidal properties. On the basis of various physico-chemical studies on octahedral geometry is assigned for the complexes.

KEYWORDS:

Cr(III); Co(II) complexes; DPCPTSC; Thiosemicarbazone; Antifungal activity


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