Synthesis and Antimicrobial Activity of 1-(4′-N-Methyl-N-Acetylamino) Phenyl-2-Phenyl-4-Benzylidine / Substituted Benzylidine-Imidazoline-5-Ones

Anjani Solankee; Kishor Kapadia; Jayesh Patel; Smurti Lad; Indrajit Thakor

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Synthesis and Antimicrobial Activity of 1-(4′-N-Methyl-N-Acetylamino) Phenyl-2-Phenyl-4-Benzylidine / Substituted Benzylidine-Imidazoline-5-Ones

Anjani Solankee*, Kishor Kapadia, Jayesh Patel, Smurti Lad and Indrajit Thakor

Department of Chemistry, B.K.M. Science College, Valsad-396 001 (India)

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ABSTRACT:

2-Phenyl-4-benzylidene/substituted benzylidene-oxazole-5-ones react with 4-amino-N-methyl acetanilide in dry pyridine to give 1-(4'-N-methyl-N-acetylamino) phenyl-2-phenyl-4-benzylidine/substituted benzylidine-imidazoline-5-ones. The synthesised compounds were tested for their antimicrobial activity. The structures of the synthesised compounds have been elucidated on the basis of their elemental analysis and spectral data.

KEYWORDS:

4-Amino-N-methyl acetanilide; Different azalactones; Antimicrobial activity